Psychedelics

Entourage effect of Peyote

The entourage effect is a phenomenon that has been gaining traction in psychedelic research. What at first was thought to be a phenomenon observed solemnly in the cannabis community and the entourage effect between THC and other phytocannabinoids turns out to be much more extensive than what we thought to be and to influence several species such as the Psilocybe genus. One specific study highlighted the significance of this phenomenon by demonstrating the superior therapeutic accuracy of psilocybin extracts compared to synthetic psilocybin.

However, there is a species that hasn’t been spoken of enough when mentioning the entourage effect. Lophophora Williamsii (Peyote).

Join us and understand the entourage effect in Peyote!

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Caribbean might become a vortex to the DMT realm

Did you know the Caribbean might become a vortex to the DMT realm?

Before the 1960s, DMT was an obscure compound in Western society, even if it had been used circa 900 CE by the Tiwanaku.

DMT is mainly known for its short duration. However, while appealing to some, others find this as an obstacle.

What if we could extend this experience to explore these realms of consciousness more in-depth?

This question formed the DMTx study by administering DMT using target-controlled intravenous infusion, a technique commonly used in anesthesia to maintain a stable drug concentration in the brain, allowing patients to have a prolonged DMT experience.

Since neither DMT nor DMTx is legal in any state, the team of Dr.Andrew Gallimore, Dennis McKenna, Graham Hancock, et al. are looking at the Caribbean islands to become a new mecca for the studies of DMT and DMTx.

The project should go live within a year, and anyone can book a week of several sessions of various lengths of DMTx and other compounds, as well as integration processes, by always prioritizing the set and setting and not just the psychedelic experience.

Now, the team is raising funds to fund an Institute and turn the Caribbean into what might be a vortex to the DMT world!

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Slow releasing Ketamine tablets might be the future for the treatment of severe depression

The notion of Ketamine being a horse tranquilizer is slowly shifting into the compound as a tool in psychotherapy for the treatment of several mental illnesses, allowing novel therapies, such as Ketamine VR and using Ketamine to treat post-finasteride syndrome, to be developed.

However, there is a downside to Ketamine therapy. Its availability, the cost, and the fact that patients stay in clinics for two hours after administration. But this might be changing soon!

Researchers are currently in clinical trials for the approval of a slow-releasing racemic Ketamine tablet that will lower the cost of Ketamine therapy and can be administered at home by the patient as it doesn’t have the typical dissociative side effects in IV Ketamine and has low chances of addiction according to researchers.

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Can blind people have visuals on psychedelics?

One of the most intriguing effects of psychedelic compounds is their capability to induce visual hallucinations. But how would it feel if someone visually or hearing impaired took a psychedelic? Would they still be able to have visual/auditory hallucinations? Compelling research says perhaps, as congenitally blind patients have proven to have visual hallucinations in near-death experiences, concepts of synaesthesia may take a role in the experience. Additionally, if the brain had access to visual-auditory data if someone lost their vision/hearing recently, there is a chance the brain may be able to generate visual/auditory hallucinations!

Proving us the wonders of neuroplasticity and Paul Bach-y-Rita’s quote. “We see with our brain, not our eyes.”

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One step closer to saving a species!

In the last five years, two words have spread like wildfire, “Toad Medicine” (5-MeO-DMT) is in the mouths of celebrities, herpetologists, psychonauts, and curious people. This curiosity narrowed Incilius Alvarius to endangerment due to poaching and increased movement on the Sonoran roads. Fortunately, researchers at Mount Sinai Hospital and Columbia University greeted us with another synthetic alternative to stop harming the toads 4-F,5-MeO-PyrT.

Could this be a queue to stop seeing this toad as a “medicine” and see it as a living species once again and stop abusing it for personal benefit?

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How psychedelics might break social media

Since the first specimens on earth, one predominant trait has a heavy presence today. The will to gain power and to be at the top.
These behavioral patterns continued throughout time and interspecies, and even today, demonstration of physical strength, financial power, or influence amuses us.

Such traits have led to an addiction to following today’s currency, which is influence, leading to addiction to social media and change in our neurochemistry.

Read more to understand the power of psychedelics on breaking habits such as constantly checking our phones, being attracted to productive capitalist ideology, and being a part of the system or the matrix.

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Psychedelic Hallucinations may be generated in our retinofungal pathway!

Psychedelics are one of the most mysterious compounds. Still today, we have plenty of questions to answer. However, we got a step closer to understanding them with the recent study published by the University of Maastricht and the team of Zeus Tipado, Kim P.C. Kuypers, Bettina Sorger, and Johannes G. Ramaekers, who brought to light a new theory that psychedelic induced hallucinations might generate in the retinofugal pathway.

Join us to uncover this hypothesis and understand the mysterious world of psychedelics.

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Psychedelics inspiring artists: A conversation with Sylocin

Without a doubt, one of the first things that comes to our minds🧠 when thinking about psych*delics is the distortion of our vision, followed by visual and auditory hallucinations. To most, these hallucinations are mere imagery or part of our hallucinations generated by our brain, but how would someone with an artistic vein perceive such changes in their sensory and neural sites?

To understand more how these compounds may influence and inspire someone’s art, we spoke to EDM music producer Sylocin🍄

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Impact of new Halogenated Tryptophan Derivatives on Psychedelic Research

Groundbreaking research has demonstrated the potential for enzymes to selectively halogenate tryptophan at the 5-, 6-, or 7- positions, with particular emphasis on the 7- position, opening up opportunities to expand bio-based production to different hosts and halogenation positions within tryptophan, making it relevant for a cheaper large-scale industrial production of tryptophan pharmaceutical derivatives.

In the realm of psychedelics, this method could lead to the development of various tryptamine-based psych*delics and new halogenated beta-carbolines that can be used as alternatives to MAOIs in pharmahuasca blends. The possibilities are vast and exciting.

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