Sustainable Psychedelic Methods

In the last five years, two words have spread like wildfire, “Toad Medicine” (5-MeO-DMT) is in the mouths of celebrities, herpetologists, psychonauts, and curious people. This curiosity narrowed Incilius Alvarius to endangerment due to poaching and increased movement on the Sonoran roads. Fortunately, researchers at Mount Sinai Hospital and Columbia University greeted us with another synthetic alternative to stop harming the toads 4-F,5-MeO-PyrT.

Could this be a queue to stop seeing this toad as a “medicine” and see it as a living species once again and stop abusing it for personal benefit?

Impact of new Halogenated Tryptophan Derivatives on Psychedelic Research

PsychedelicsASL

Groundbreaking research has demonstrated the potential for enzymes to selectively halogenate tryptophan at the 5-, 6-, or 7- positions, with particular emphasis on the 7- position, opening up opportunities to expand bio-based production to different hosts and halogenation positions within tryptophan, making it relevant for a cheaper large-scale industrial production of tryptophan pharmaceutical derivatives.

In the realm of psychedelics, this method could lead to the development of various tryptamine-based psych*delics and new halogenated beta-carbolines that can be used as alternatives to MAOIs in pharmahuasca blends. The possibilities are vast and exciting.

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One step closer to saving a species!

Impact of new Halogenated Tryptophan Derivatives on Psychedelic Research