PTSD

Slow releasing Ketamine tablets might be the future for the treatment of severe depression

The notion of Ketamine being a horse tranquilizer is slowly shifting into the compound as a tool in psychotherapy for the treatment of several mental illnesses, allowing novel therapies, such as Ketamine VR and using Ketamine to treat post-finasteride syndrome, to be developed.

However, there is a downside to Ketamine therapy. Its availability, the cost, and the fact that patients stay in clinics for two hours after administration. But this might be changing soon!

Researchers are currently in clinical trials for the approval of a slow-releasing racemic Ketamine tablet that will lower the cost of Ketamine therapy and can be administered at home by the patient as it doesn’t have the typical dissociative side effects in IV Ketamine and has low chances of addiction according to researchers.

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One step closer to saving a species!

In the last five years, two words have spread like wildfire, “Toad Medicine” (5-MeO-DMT) is in the mouths of celebrities, herpetologists, psychonauts, and curious people. This curiosity narrowed Incilius Alvarius to endangerment due to poaching and increased movement on the Sonoran roads. Fortunately, researchers at Mount Sinai Hospital and Columbia University greeted us with another synthetic alternative to stop harming the toads 4-F,5-MeO-PyrT.

Could this be a queue to stop seeing this toad as a “medicine” and see it as a living species once again and stop abusing it for personal benefit?

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Harm reduction 101: The harm reduction guide

This harm-reduction series will be sharing tips on how to have safe trips. Covering subjects such as psychedelic therapy, and psychedelic retreats, the importance of testing your compounds, set and setting, and the importance of having a plan and using a trip sitter.

In this chapter, we will be focusing on the importance of testing your substances and when to use each reagent, what is set and setting and their importance, the importance of tripsitters (buddy-system), and how to create a safety plan when using psychedelics.

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Harm reduction 101: Psychedelic therapy and psychedelic retreats

This harm-reduction series will be sharing tips on how to have safe trips. Covering subjects such as psychedelic therapy, and psychedelic retreats, the importance of testing your compounds, set and setting, and the importance of having a plan and using a trip sitter.

In this chapter, we will be covering the misconception of psychedelics alone being able to heal mental illnesses, and the processes behind psychedelic therapy, including what is integration, types of integration, and how to be safe in international retreats.

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Stories of a modern opioid eater

From Daquince’s use of opium to the modern era, many stories of opioid users have been lost. For that reason, we cover the stories of two opioid- users Benzzzy and Calvin, from what led them to their addiction, their difficulties during this period, their advice for people who might be going through addiction, and their current status.

In addition, we discuss the pharmacology student Anthony Furrule (@science_and_anonymous) about opioid prescription, opioid alternatives, the use of Ibogaine or its analogs for the treatment of addiction, and Narcan-resistant Fentanyl.

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Origins of Ethnopharmacology

Aspirin, Digoxin, and Morphine aren’t the first thing that comes to our minds once we hear the word Plant Medicine. Regardless of their seemingly distant origin, all those compounds once had a plant origin. To this, we name ethnopharmacology. Using the word of Juerg Gertsch: “Ethnopharmacology tries to understand the pharmacological basis of culturally important plants.”

Today, ethnopharmacology has an equally important role, as we are using plants that have been used for centuries by natives. Plants such as Peyote, Ayahuasca, Iboga, Kava Kava, and Psilocybe aid us with the current mental illness epidemic. Thus, Indigenous communities are once again furnishing us and aiding us with their ancient knowledge, this being said it would only be unfair not to feature such communities in Psychedelic and Ethnobotanical conferences, giving them their due credit, and teaching us about how much these plants mean to their culture, and most importantly how we should respect and protect indigenous rights.

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The new religion of Psilomethoxin

The new internet-breaking tryptamine Psilomethoxin has generated various discussions on threads. Following breadcrumbs left by Alexander Shulgin, the owners of the Psilomethoxin church claimed to have successfully made the compound and report several experiences using it.

However, the discussion continues, from being a 4-hydroxylated orally active form of 5-MeO-DMT to a potential neurotoxin for its similarities to 4,5-dihydroxytryptamine it’s yet incognito whether the compound could have any neurotoxicity.

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