LSD

JRT a new Lysergamide in the Horizon?

By altering the position of two atoms in the molecular structure of LSD, a team at UC Davis created the new compound named JRT and published the discovery on April 14th, five days before Bicycle Day.

The subtle change preserved the ability of the drug to stimulate brain cell growth and repair damaged neural connections, key features in treating cognitive decline while minimizing the psychedelic effects.

When given to mice, JRT has powerful neuroplastic effects and improved measures of the negative and cognitive symptoms of schizophrenia without showing behaviors and gene expression associated with psychosis.

“The development of JRT emphasizes that we can use psychedelics like LSD as starting points to make better medicines. We may be able to create medications that can be used in patient populations where psychedelic use is precluded.” – David Olson, director of the Institute for Psychedelics and Neurotherapeutics and professor of chemistry, biochemistry, and molecular medicine at UC Davis.

Find out more here!

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Through the Looking Glass with Laguna Meth

This week, we talked with Michael from Laguna Meth.

After his first experience with a Bart Simpson tab, his way of viewing the world switched, and so did his stance on these compounds.

What he thought were substances for the weak changed his life by allowing him to see the facade forced into his mind by the media and schools since birth and pursue something more powerful.

Music.

Read more here!

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Remembering Roland Griffiths

The heartbreaking news of Dr.Roland Griffiths’s passing was given to the world yesterday, October 17th. Griffiths was diagnosed with Stage 4 metastatic colon cancer at 76.

Despite his diagnosis to be terminal, he remained optimistic about existence. In an interview with the New York Times, he reminded us that we all are mortal quoting. “We all know that we’re terminal.”

Dr.Griffiths was an illustrious psychopharmacology professor at Johns Hopkins and spent decades studying the mechanism of mood-altering drugs. During his research, he published over 400 scientific papers on opiates and cocaine, sedatives and alcohol, and nicotine and caffeine.

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LSD lemurs and millipedes with Daniela Bolanos Garcia

The case of Professor John Buettner-Janusch is the biggest scandal around the University of NY, from synthesizing one kilo of Quaaludes and LSD to supposedly give to lemurs (where he gained his nickname Professor Quaalude) to attempting to poison the federal judge responsible for his case. Janusch claimed he had given LSD and Quaaludes to his primates to study their emotional behavior while under the influence of these compounds. However, in the wild, we have also heard that lemurs get high using hallucinogenic millipedes. To get down to these claims, we had a conversation the Tropical Biology student Daniela Bolanos Garcia to understand why they do it, whether they are consciously getting high, and what makes them high!

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