Biochemistry

Meet the Fireside project App: Your virtual Peer Support Line

Psychedelic experiences are a trip into the unknown and sometimes get out of hand or become too much to decompress or at least on your own.

Fireside Project considered this and created the first app to help us during and after our trips, with over 100 volunteers to provide you with non-clinical emotional support, giving you a compassionate experience filled with knowledge about the psychedelic realms while always protecting your identity without collecting personal data.

The Fireside Project line is open every day from 11:00 a.m. to 11:00 p.m. PT to everyone in the United States!

Most importantly, it’s free and one click away!

Read more here!

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Our field guide to enter the Psychedelic Space

During my journey of a decade, I’ve met a lot of people who knew about psychedelics, but only a smaller group of people dedicated their lives to educating themselves about these compounds.

When starting your journey, it’s hard to distinguish between the two as every piece of knowledge may seem like a golden nugget. (I assume nowadays it is even more confusing to differentiate the two with the rise of AI tools such as ChatGPT.) 

For this reason, we decided to present you with our field guide to let you know what you should do if you are trying to integrate into the psychedelic space.

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Novel concept of Entheogenic Synergy

Following up on last week’s article, we clear up what we coined as Entheogenic Synergy, which bifurcates into Recreational Synergy and Therapeutic Synergy, concepts intended to raise awareness of anthropological values, mu beliefs, and elements susceptible to changing our biochemistry, microbiota, neurochemistry, and the way we think, such as music, hearing other experiences, expectations, and the journey to our destination, as well as conversations we have about the experience, being present to a new environment and language, learning to adapt, changing our neuroplasticity and thermoregulation are explored as equally as the psychedelic experience, and even further, be included in the psychedelic experience in the future research. 

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Entourage effect of Peyote

The entourage effect is a phenomenon that has been gaining traction in psychedelic research. What at first was thought to be a phenomenon observed solemnly in the cannabis community and the entourage effect between THC and other phytocannabinoids turns out to be much more extensive than what we thought to be and to influence several species such as the Psilocybe genus. One specific study highlighted the significance of this phenomenon by demonstrating the superior therapeutic accuracy of psilocybin extracts compared to synthetic psilocybin.

However, there is a species that hasn’t been spoken of enough when mentioning the entourage effect. Lophophora Williamsii (Peyote).

Join us and understand the entourage effect in Peyote!

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The new religion of Psilomethoxin

The new internet-breaking tryptamine Psilomethoxin has generated various discussions on threads. Following breadcrumbs left by Alexander Shulgin, the owners of the Psilomethoxin church claimed to have successfully made the compound and report several experiences using it.

However, the discussion continues, from being a 4-hydroxylated orally active form of 5-MeO-DMT to a potential neurotoxin for its similarities to 4,5-dihydroxytryptamine it’s yet incognito whether the compound could have any neurotoxicity.

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