September 2026

An 80-year-old woman with advanced Alzheimer’s regained speech and mobility after taking psilocybin

An 80-year-old woman with advanced Alzheimer’s regained speech and mobility after taking psilocybin​

A Japanese-American woman in her 80s was mostly monosyllabic, accompanied by severe reduction in spontaneous interaction, chronic urinary incontinence, executive dysfunction, impaired mobility, dysphagia, and dependence in activities of daily living. But after being given 5 grams of Psilocybin containing mushrooms in a clinical setting, she “spontaneously initiated autobiographical conversations lasting several hours”. In the following days and weeks, she regained urinary continence, walked more independently, became more alert, recognized her family, and was able to dress herself.

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