Natural from the Sierra Mazateca, Salvia Divinorum is well known amongst Shamans, however, not much is known about the variations within the species remaining a chemical mystery.

Since the pre-Hispanic times, tribes such as the Zapotecs, Chinantecs, Mazatecs, and Mixtecs used Morning glory seeds (Ololiuqui), despite the hallucinatory and vasoconstriction effects, E.T Brady Jr from the Ross General Hospital believes the effects can be reversed using chlorpromazine in addition to psychiatric consultation to aid mental health building a bridge between ancient shamanism and modern psychopharmacology.

Despite its popularity as a party drug cocaine has chewed and consumed an ash mixture going by the name of Mambe by various indigenous tribes in the Amazon rainforest and clinically in western societies for centuries, these practices remained until today reasoning why the compound remains a Schedule II drug.

A story of how the Blue Lotus influenced cultural-religious beliefs and took part in religious orgies in Egypt and its progression to our modern Pharmaceuticals.

As the Pandemic progresses, the use of Opioids raised massively, with the increase of built-in stress, augmentation of cases of depression, anxiety, and ADHD, people often search for alternatives for their prescribed medication as they are afraid to get hooked into it. In 2020 Kratom took a major step towards its legalization, further information will be discussed by the Royal Thai Gazette, recent studies predict the binding to and Allosteric Modulation of the μ-Opioid Receptor by Kratom’s Alkaloids and users claim that Kratom could be an alternative for their prescription for their mental health.

A duality of realities from two different types of tobacco consumerism, the contrast between the use of the plant in Native American tribes where the plant is considered sacred and the use in Western Societies where the plant is known to be an addiction.

A repertoire of my experience with sensory deprivation tanks, firstly invented by John C.Lilly.

Virola snuff has been a part of various tribes over the years for its shamanic use, despite the first belief that the active compound in the substance was myristicin, considerably an MMDA metabolite present in several culinary delicacies, the main psychoactive compound is proven to be 5-MeO-DMT.

Brugmansia, another species slandered by the media, known for its use in Colombia as the Rape drug and yet the paradox praising it has a nausea medicine to aid surgery and its use as a truth serum in military operations.

Welwitschia mirabilis has recently been studied, presenting a curious genetic causing its "Immortality" presenting a general bettering towards cultivation and home cultivation of various species indicating a way to prevent the extinction of plants due to global warming.