Psychedelics

Eleusis the first luxury psychedelic retreat is hosting DMTx, here is what you need to know

Eleusis the first luxury psychedelic retreat is hosting DMTx, here is what you need to know!​

Eleusis the first luxury psychedelic retreat is hosting DMTx, here is what you need to know! By Goncalo V. What if we could further explore DMT realms in more depth? Understand who these entities are and why we see them in the DMT experiences, and uncover why so many people experience witnessing entities on DMT in comparison to when taking other compounds. What if DMT is a vortex to another reality hidden within our brains? These were all questions fomented to create Eleusis, following the research model for the Application of Target-Controlled Intravenous Infusion for a Prolonged Immersive DMT Psychedelic Experience (DMTx) by Dr.Andrew Gallimore and Rick Strassman. This model uses target-controlled intravenous infusion (TCII), a technique commonly used in anesthesia to maintain a stable drug concentration in the brain. By leveraging pharmacokinetic modeling and DMT blood sampling data, the researchers demonstrated that DMT’s rapid onset and lack of acute tolerance would make the compound suitable for TCII. Allowing patients to have a prolonged DMT experience enables detailed observation and analysis of its psychological effects. Eleusis will debut this month on the island of Bequia in Saint Vincent and the Grenadines, thus becoming a new mecca for the study of DMT and DMTx, alongside Dr. Andrew Gallimore, Dennis McKenna, Graham Hancock, and other personalities.   What is DMT, and what is its history?   Until the 1960s, DMT was an obscure compound in Western society, despite its use dating back to circa 900 CE by the Tiwanaku, one of the most significant Andean civilizations. In 1931, the compound entered Western civilizations. Richard Manske was responsible for first studying DMT when searching for derivatives of N-methyltryptamines. However, the effects of the compound were only observed years later by Stephen Szara, after he extracted the compound from Mimosa Hostilis root bark and injected it into himself. Such research brought attention to various minds, such as the McKenna brothers, Dennis and Terence McKenna, Terence who ended up pioneering the experiences of DMT in the psychonaut community through his lectures and description of machine elves, fractals, alien patterns, during the ’60s, followed by various reports of psychonauts claiming to have seen various fractals, aliens, or even religious figures that would give them alien knowledge about the world, or give them answers (read more about DMT here).  Stanislav Grof and Wim Hof developed breathing techniques meant to increase the biosynthesis of DMT in the body. Rick Strassman opened the doors to research and literary piece “DMT: Spirit Molecule”, and lately, Andrew Gallimore followed up with his work on DMT alien worlds and DMTx alongside a broad team Show your love for the spirit molecule Apparel DMT: Consciousness Expedition Unisex T-Shirt $45.00 Apparel DMT: Consciousness Expedition Unisex Sweatshirt $65.00 Apparel DMT: Consciousness Expedition Unisex Hoodie $80.00 Apparel DMT Shulgin Handwritten Molecule Dad hat $45.00 Getting to the bottom of the question. Is DMTx safe? Eleusis has safety as its highest priority. To achieve this, they have a few bullet points to ensure the safety of their patients: If a patient feels uncomfortable or wishes to end their journey, the clinical team can stop the infusion. After the infusion is stopped, the experience will stop within minutes, allowing people to return to their normal state quickly and safely. Every session is medically supervised by physicians and clinical staff with advanced monitoring and immediate support. Their protocols are conducted with a fully legal framework and high standards of integrity and care. Sessions include thorough pre-retreat health and psychiatric screening, personalized preparation, and ongoing integration support. (Read more about the importance of set and setting here.) While Eleusis provides such points for the DMTx experiences of their patients, we must note that DMT is not a perfect molecule that is or should be experienced by everyone. Below, we will give you some examples of some occasions when you should avoid a DMT experience or discuss the idea with your doctor before embarking on your DMTx journey: Individuals with Certain Pre-existing Mental Health Conditions (such as schizophrenia, or Bipolar I Disorder, or who have first-degree relatives with these psychiatric conditions.) Individuals on Certain Medications or Drugs (for example, SSRIs) Immunocompromised Individuals (for example, cardiovascular disease) Pregnant or Breastfeeding Individuals Have a safer trip with Miraculix Buy your test kit here   The team:   Eleusis is composed of some familiar faces if you’ve been in the psychedelic space for some time. Some we’ve previously mentioned in this and other articles, such as Dr. Andrew Gallimore and Dr. Chris Timmermann, but there are far more familiar faces that constitute the Eleusis team, Bianca Abbott, Carl Hayden Smith, Dr. Murray Heber, and Dr. Andrew Ferber in the medical and R&D departments. Ian Mccal, Michael Smith, Jordan Poyer, Michael Gonzales, Savej, Chris Dyer, and WALLY are the program leaders and advisors. The Executive Team was formed by Angus Taylor, Craig Strenhouse, Christina Thomas, Charles Patti, and Kirstie Wilkins. (You can meet the Eleusis team here: https://eleusismind.com/about)   Outside of the trip: The six-day experience at Eleusis is fully inclusive, allowing you to focus on your DMTx experience and make the most of it to heal and explore the human mind. Covering comprehensive medical and psychiatric screening using tools such as: HUME band and bimetric data Personalized integration Pre-retreat materials 3 DMTx experiences Daily group integration Yoga sessions Meditation Luxury accommodation in private villas or suites Gourmet, organic meals and beverages 4 weeks of post-retreat integration calls (learn about the importance of integration in our interview with Dr. Victoria Sterkin) Guests with limited availability can also book a fully inclusive 4-day experience that includes two DMTx experiences. For those interested in DMTx, you may follow this link to book a call with the team and apply for the retreat: https://form.jotform.com/250685241546156 For more information about Eleusis, follow this link: https://eleusismind.com/ As always, stay safe, sending love. About the author Goncalo V Goncalo V. founded Psychedelics As a Second Language (PsychedelicsASL) in 2021 with the aim of making psychedelic science available and understandable for everyone,

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Why do psychedelics alter our perception of time, and how could that affect Psychedelic therapy?

Why do psychedelics alter our perception of time, and how could that affect Psychedelic therapy?

Why do psychedelics alter our perception of time, and how could that affect therapy? By Goncalo V. Time perception is potentially one of the most present skills in our day to day, we’re constantly aware of time during our circadian routine, whether it’s to enter our routine or finish our day, yet this is only part of what time perception actually does in our life, time perception has profound effects on human consciousness, influencing cognition, affect regulation and behavior. Typically speaking, we perceive life as a continuous timeline — yet, the perception of time allows us to determine how we perceive the past, present, and future, thus affecting our sense of self and what is real. However, when someone consumes a psychedelic compound like DMT, LSD, or even Salvia Divinorum, their perception of time can change to the point where they claim to believe that they’ve experienced hours, and sometimes even decades of their life, or even eternity when tripping, a phenomenon known as time dilation. Such distortions in the perception of time offer us insight into how the brain processes time. They disrupt the assumptions of traditional models of consciousness. This reminds us how something as essential as time can be. What happens to our brain when we lose perception of time is where things become interesting. To understand more about how the perception of time changes between psychedelic experiences, we will go through three typical scenarios reported by the psychedelic community. Slowing down of time Speeding up time Feeling of Timeless/Eternity The perfect choice for those who love exploring the mind Apparel Exploring the Mind Embroidered Vintage corduroy cap $45.00 Apparel Exploring the Mind Embroidered Unisex Hoodie $80.00 Apparel Exploring the Mind Embroidered Unisex Sweatshirt $65.00 Apparel Exploring the Mind Embroidered Short-Sleeve Unisex T-Shirt $45.00 Typically speaking, psychedelics make users experience a slowing down of time— this change is attributed to increase sensory processing, as psychedelics elevate neural oscillations in lower brain regions, which are responsible for sensory input and emotional processing. Additionally, the augmented attention to sensory stimuli during a trip can also interfere with time perception as the brain attempts to process information at a higher rate. But on the other side of the coin, some people describe hours passing like minutes. This could be linked to what the psychonaut community calls “ego dissolution,” which can loosen someone’s perception of time. For this reason, it’s believed that time compression could be caused by the alteration in serotonin levels and consequent effect on the cortical activity via the 5-HT2A receptor. The third-mentioned hypothesis is the effect of timelessness itself, a complete dissociation of the passage of time, once this happens, users typically describe profound or mystical experiences, and it’s believed that this might be a products of changes in the default mode network (DMN) of the brain, as the default mode network is associated with self-referential thinking and perception of continuous time, its suppression during these altered states could result in the dissolution of time as a boundary, past, present and future are perceived as irrelevant or a unified moment. As every human body reacts differently to these compounds and the sense of temporal distortions, these experiences can vary depending on the type/class of compound, dosage, and setting. Additionally, distinctions between compounds bring up the possibility that different pharmacological interactions could be the key to understanding such modifications to time perception, at least amongst psychedelics, demonstrating that the neural substrates that mediate these experiences are multifaceted. Such alteration in the perception of time while in psychedelic states could provide a novel perspective to study the brain mechanisms in temporal processing, and pave new perspectives for the study of the role of consciousness and its influence in what we consider reality. But first, we must address the big elephant in the room: How do psychedelics alter our perception of time? Our ability to understand time perception is influenced by the activity of distributed brain regions, neurotransmitters, and neural synchrony. Basal ganglia: Implicated in interval timing on the scale of hundreds of milliseconds, functioning as a putative internal clock, generating temporal predictions based on sensory evidence.   Prefrontal Cortex: Encodes longer time spans and combines information for planning and making decisions. Crucial for controlling dynamic time-based tasks.   Cerebellum: Refines motor coordination and precise timing by integrating sensory input and motor output for precise timing events. By integrating interception of internal body states with cognitive perception, the insula has a modulating role in how emotions and somatic sensations shape our perception of time. Neurobiological mechanisms of psychedelic-induced time perception alterations.   These processes are further regulated by major neurotransmitter systems. Dopamine: Acts primarily through the basal ganglia and modulates short-interval timing. Dysregulation is linked to timing deficits.   Serotonin (particularly via the 5HT2A receptor activation): Influences longer time scales. Is the primary mediator of psychedelic-induced time distortions Interfacing emotional and sensory processing with subjective time experience.   Glutamate (largely through the NMDA receptor-mediated neurotransmission): Supports the neural encoding and maintenance of precise temporal representations needed for various cognitive tasks. Write with us Our mission is to educate about psychedelics. Whether you’re sharing your personal journey, exploring science, or crafting tales of transformation, your voice matters here! Pitch us your idea via email In order to have a precise time perception, there must be a temporal coordination of neural activity between distant brain areas (generally mediated by neural synchrony), almost like a neurobiological orchestra within our body; these rhythms allow the synchronicity of sensory, motor, and cognitive activities. Once we disrupt the synchronicity, it may result in a distorted perception of time. This is exactly what happens when we take a psychedelic compound: it strongly affects the rhythm of this orchestra, resulting in the disrupted time perception due to the modulation of the brain’s sensory, calm, and self-reference system. One key factor for the mediating role of these changes is the Default Mode Network (DMN), comprised of: Medial prefrontal cortex, Posterior cingulate Angular gyrus Related to self-referential thinking and

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Lanmaoa Asiatica lilliputian hallucinations or an anthropological phenomenon?

Lanmaoa Asiatica lilliputian hallucinations or an anthropological phenomenon?

Lanmaoa Asiatica lilliputian hallucinations or an anthropological phenomenon? By Goncalo V. In January 2026, a mushroom began to appear in various news outlets after its appearance on the BBC due to its unique effects, Lanmaoa asiatica. When mentioning mushrooms and hallucinations, our brain automatically says it’s either psilocybin (from the psilocybe genus) or muscimol (from Amanita Muscaria); however, once we analyze trip reports from these compounds, they often don’t follow a pattern, even if ingested multiple times throughout our lifespan, making these trips “unpredictable” in the sense of we cannot predetermine what the peak of our trip will look like, especially when mentioning visual hallucinations. However, things are far different when mentioning Lanmaoa asiatica. Unlike the unpredictability of visual effects in other mushrooms and psychedelics, doctors at hospitals in the Yunnan Province of China (the natural habitat of Lanmaoa asiatica) report hundreds of cases every year, with 96% of the patients having the same visions of “tiny people” or “elves”, dancing, jumping, or marching around the environment. Here’s where things become interesting… How do people obtain these mushrooms, and what causes these hallucinations? Surprisingly, Lanmaoa Asiatica is one of those mushrooms that lived for ages under everyone’s radar until 2014, when a group of mycologists in Yunnan purchased and sequenced the mushroom, making it a species known to science. During the sequencing and understanding of the mushroom in the eyes of science, something rather unique was found. Lanmaoa Asiatica is more closely related to Porcini (Boletus edulis) than any known psychedelic mushroom species. Where people get these mushrooms might also surprise you, as these fungi aren’t scheduled; they can still be bought in open-air street markets and are present on restaurant menus when in season, despite reports from hospitals and warnings.   The reason why lies in the cultural and folk knowledge surrounding the mushroom and its hallucinatory effects, while the species is fairly recently acknowledged by science, Lanmaoa Asiatica, like Ayahuasca, once had deep ancient roots in the Chinese culture, with data remoting to Daoist texts from the 3rd century CE refering to a flesh spirit mushroom that if consumed raw allows people to “see a little person” and “attain transcendence immideatly”. “If you see a little person seven to eight cun 寸 [3-33cm] tall riding in a carriage when you travel on a mountain, you have encountered a flesh spirit mushroom. Consume it raw, and you will attain transcendence immediately.” – Daoist Ge Hong (~300CE) – The Master Who Embraces Simplicity 抱朴子:] “Rou zhi 肉芝 (Flesh Spirit Mushroom). Meet our Ecstasymon- Limited Edition collection While what makes the mushroom hallucinatory is still unknown to science, this quote actually brings us more clues to what makes the mushroom cause hallucinations than we might think, and so users on the notorious psychonaut forum Bluelight caught up to this little detail and began speculating about what could be the compound responsible for such lilliputian hallucinations using the data and the chemical composition of the mushroom we currently have available.   The one thing that interested us the most during these discussions circles back to the fact that such a high percentage of people in the region feel the same effects when eating the mushroom raw, or even when not prepared correctly.   As mentioned by users in the forum, we could be looking at a novel compound with novel interactions that change our perception of sight and dimension, something quite similar to AIWS (Alice in Wonderland Syndrome), known to cause micropsia (objects or people appearing smaller than usual), but what if something of an anthropological value of having such belief so ingrained in their folklore and culture for at least more than 1700 years has influenced and shaped the way they portray such visions?   To some, this could seem like a stretch, but in reality, it’s slightly more common than you might think and has happened more times than we can count, especially in isolated tribes whose culture shapes their life and way of living. One brief example would be the constant reports of Ayahuasceros and indigenous tribesmen hallucinating about becoming a serpent, or a jaguar, upon consuming Ayahuasca, which are heavily linked to their claims that the mother of Ayahuasca is a serpent(linking to the fact that the serpent is the most sacred animal for many tribes, representing strenght, healing, and wisdom), and the jaguar being a link to the belief that shamans could become jaguars or gain their spirit to protect their community, hunt down dark sorcery, or guide participants during their experiences. It’s undeniable that such cultural effects, histories we’ve heard that stick with us, are likely to manifest during these experiences. Another prime example of how these stories affect our subconsciousness is Terence McKenna’s description of the machine elves and the reports of people describing the exact same beings years after hearing Terence’s speech. While some may argue that these beings truly exist in the DMT world, I believe we should ask ourselves whether this could be an anthropological event, which is a concept we’ve been exploring in our upcoming book Entheogenic Synergy (you can find more about it here, and you may also send in your report in the form below!) We need your help We are currently working on our second book, Entheogenic Synergy. To do so, we need your help. By sharing your psychedelic experience, you will be helping us immensely with our study to prove the theory that external factors before the psychedelic experience can impact the way we trip. You can share your psychedelic experience by accessing our form. Fill the form About the author Goncalo V Goncalo V. founded Psychedelics As a Second Language in 2021 with the aim of making psychedelic science available and understandable for everyone, regardless of their background and scientific knowledge. Since then, he has interviewed various guests within the psychedelic field, including artists, psychedelic entrepreneurs, chemists, psychedelic researchers, therapists, and students, all with one goal. To give you an organic and raw experience of

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AI-Generated Trips, the future of psychedelic therapy or more AI slop?

AI-Generated Trips

AI-generated trips: The future of psychedelic therapy or AI slop? By Goncalo V.   Following last week’s article, the concept of generating trips is in its prime, arguably more than we thought, but with a different approach than the Trip Movies. The team of Giuseppe Riva, Giulia Brizzi, Clara Rastelli, and Antonino Greco presented the possibility of simulating experiences with psychedelics using AI-Generated imagery and integrating it in therapeutic frontiers.   It’s undeniable that AI has made its way into our lives abruptly. At first, many were scared as Sci-Fi movies constantly warned us of a future robotic takeover — but instead, we are currently facing an intellectual takeover by the various platforms of AI. From asking ChatGPT what we should do for breakfast, to asking them to become our mentors, therapists, or even using other AI tools to generate art, there is one specific computer vision program (now also powered by AI) that has been around for decades, that has evolved to translate into something different,  to create images using convolutional neural network to find and enhance patterns in images using algorithmic pareidolia, creating a dream-like appearance that reminded users of a psychedelic experience by generating over processed images, a program which the Google engineer Alexander Mordvintse named DeepDream. Shulgin Farm- Image by the Shulgin Foundation DeepDream version of the image   While some images may seem an overkill when it comes to computer generation, as typically, psychedelic trips can be far more subtle when it comes to changing our visual perception of things, the example shown above, is obviously one of the most overkill examples, DeepDream also provides us with options far more subtle that could resemble what people would perceive the world in highly visual hallucination inducing compounds such as DMT including some geometrical shapes and kaleidoscopic features. Such resemblances between the visuals in psychedelic trips and the images generated by DeepDream were what fueled the research by Giuseppe Riva, Giulia Brizzi, Clara Rastelli, and Antonino Greco — by picking up the engine that allowed people make trippy images for decades, we could now allow people to experience “psychedelic visuals” without actually having to take the compound. For those who love researching psychedelics: Apparel Researching Psychedelics Embroidered Vintage corduroy cap $45.00 Apparel Researching Psychedelics Embroidered Unisex Hoodie $80.00 Apparel Researching Psychedelics: Embroidered Unisex Sweatshirt $65.00 Apparel Researching Psychedelics Embroidered Short-Sleeve Unisex T-Shirt $45.00 Now they only needed to find one answer: how can we make this experience immersive to the user without feeling like we are just staring at an LCD or AMOLED screen, and how does this translate into replicating an actual psychedelic trip? To achieve an answer to these questions, the team picked on the concept on how, during VR experiences, the brain attempts to predict the sensory consequences of an indivual’s movements providing them the same scene they will see in the real world, therefore, the brain maintains a model (in this case, the simulation) of the body and the space around it.   But how would this play out in the real world?  Can changing realities affect our neurochemistry and have real therapeutic effects?   To the surprise of many, messing up with how we view the world, even if it is for a short period of time during a VR session, modifies the same predictive coding mechanism that makes classic psychedelics therapeutically effective, and the team noticed that participants exposed to these AI-generated experience demonstrated increased cognitive flexibility, additionally, the experiences reduced positive affects and state of anxiety, reduced heart rate and sympathetic activity compared to baseline. Such changes appear to work by modifying the same predictive coding mechanism that makes classic psychedelic therapeutically effective. Write with us Our mission is to educate about psychedelics. Whether you’re sharing your personal journey, exploring science, or crafting tales of transformation, your voice matters here! Pitch us your idea via email These predictive coding mechanisms enable the brain to function as a predictive machine by constantly generating predictions about sensory inputs, thereby balancing previous beliefs and incoming information. According to the REBUS model, psychedelics induce a relaxation of rigid priors, which are primarily mediated by the 5-HT2A receptors; the imbalance between what is expected and what is coming leads then to hallucinations. Considering the concept of similarities between simulated and substance-induced hallucinations of perception, emotional responses, and cognitive flexibility, there is a chance that “Cyberdelics” could have a similar effect, that the nature of AI-generated content could cause a temporary recalibration of the precision weighting process, and sensory data are considered more reliable than priors. Thus, allowing “Cyberdelics” to facilitate a form of cognitive relaxation that aligns with the principles of the REBUS model. https://www.youtube.com/watch?v=AaTjty1unn8&t=2783s   The pros and cons: If “Cyberdelics” are proven to work, they could be a solid foundation for future psychedelic therapy, as they: Don’t require a prescription. There are no legal barriers stopping this research. Waiting lists should be minimal. Every session can be customized. Previous patients can revisit prior “trips” and access them as therapeutic material post-experience. The cons: The amount of exposure needed for a lasting change is unknown. It’s unknown whether these experiences can have a therapeutic effect without the guidance of professionals. Integration in the psychedelic community and general society: When talking about psychedelic experiences, or taking psychedelics, the most predominant idea that automatically pops into people’s minds is the crazy visuals, the mind-bending perceptions of reality, the epiphanies that will make you rethink every choice you made in life, re-live it, and allow you to change your perception of life or even meeting God or other spiritual entities that will uncover and decode the secrets of the world to you. While this can sometimes happen, we must question ourselves whether these visuals are the only thing relevant when it comes to a psychedelic experience. To do so, we invite you to read one of our previous articles regarding how blind people react towards the effects of psychedelic compounds (Read here) We also wanted to

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After 100 years of propaganda Cannabis could be moved to Schedule-3

From being the “Assassin of Youth” to “Devil’s Lettuce”, a small green plant with its unique leaf shape, Cannabis has been the target of a century of propaganda tied to racial and social status discrimination. While still present in certain generations impacted by propaganda, this ideology is slowly changing in society. In May 2024, the DEA proposed to rule to move Cannabis from Schedule 1 to Schedule III. This situation was updated this year in a series of interviews on Capitol Hill in October. Learn how this can change not just Cannabis laws but potentially psychedelic laws in the future.

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